Fertility Research

New Study Reports Presence of Varicocele or Varicocelectomy do not alter ICSI Outcome Studies have shown inconsistent results regarding the effect of varicocele and its surgical correction on fertility and ART outcome. Now, a retrospective study has reported that the presence of varicocele and varicocelectomy does not outcome after ICSI. Fábio Firmbach Pasqualotto, a professor at...
FertiQoL Tool Effective in Analyzing Quality of Life in Infertile Couples A recent survey has validated the usefulness of the fertility quality of life (FertiQoL) tool in identifying the impact of infertility on the wellbeing of couples, which would in turn enable healthcare providers to better address patient concerns and improve treatment outcomes. Jacky Boivin,...
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Androstenedione induces abnormalities in morphology and function of developing oocytes, which impairs oocyte meiotic competence Objective: To obtain insight into the effects of androstenedione on ovarian folliculogenesis and oogenesis.Design: Experimental study.Setting: St. Marianna University School of Medicine.Animal(s): Prepubertal (14-day-old) BDF1 female mice.Intervention(s): Early secondary follicles were isolated...
Human spermatozoal RNAs Objective: To provide a focused review of the scientific literature pertaining to spermatozoal RNA.Design: Review of the literature and appraisal of relevant articles.Setting: Not applicable.Patient(s): Infertile male.Intervention(s): None.Main Outcome Measure(s): Spermatozoal RNAs as potential...
Epigenetics of the male gamete Objective: To review and summarize the current understanding of the epigenetic status of human sperm in regards to protamination, specific localization and modifications of retained histones, and DNA methylation.Design: Review of the relevant literature.Setting: University-based clinical and...
Semen analysis: looking for an upgrade in class Objective: To review the literature database regarding current methods for diagnosing male subfertility and to critique new testing methods that have the potential to be incorporated as part of routine semen analysis.Design: Literature database review.Setting: None.Patient(s): None.Intervention(s...
Development and current applications of assisted fertilization Since the very early establishment of in vitro insemination, it became clear that one of the limiting steps is the achievement of fertilization. Among the different assisted fertilization methods, intracytoplasmic sperm injection emerged as the ultimate technique to allow fertilization with...
Contemporary aspects of male gamete (dys)function: aiming towards optimizing the treatment of fertilization disorders At its inception, in vitro fertilization (IVF) was a relatively straightforward procedure encompassing the in vitro insemination of surgically retrieved oocytes and the trans-cervical uterine placement of the ensuing embryos with the goal of overcoming tubal infertility. Since that time, IVF has...